产品详情
This antibody detects endogenous levels of GRK1/2 (Phospho-Tyr13) at Human, Mouse,Rat
免疫原详细信息
Synthesized peptide derived from human GRK1/2 (Phospho-Tyr13)
相关试剂
Liquid in PBS containing 50% glycerol, and 0.216% sodium azide.
背景
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008],
