产品详情
This antibody detects endogenous levels of ROR1 at Human, Mouse,Rat
免疫原详细信息
Synthesized peptide derived from human ROR1
相关试剂
Liquid in PBS containing 50% glycerol, and 0.10% sodium azide.
背景
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012],
