产品详情
Phospho-Erbin (Y1104) Polyclonal Antibody detects endogenous levels of Erbin protein only when phosphorylated at Y1104.
免疫原详细信息
Synthesized phospho-peptide around the phosphorylation site of human Erbin (phospho Tyr1104)
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
