产品详情
PHX2A Polyclonal Antibody detects endogenous levels of protein.
免疫原详细信息
Synthesized peptide derived from human protein . at AA range: 210-290
相关试剂
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
背景
paired like homeobox 2a(PHOX2A) Homo sapiens The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008],
