产品详情
N2DL2 Polyclonal Antibody detects endogenous levels of protein.
免疫原详细信息
Synthesized peptide derived from part region of human protein
相关试剂
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
背景
This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq, Jul 2015],
