产品详情
OCLN Polyclonal Antibody detects endogenous levels of protein.
免疫原详细信息
Synthesized peptide derived from part region of human protein. AA350-400
相关试剂
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
背景
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011],