产品详情
This antibody detects endogenous levels of PDLI2 at Human/Mouse/Rat
免疫原详细信息
Synthesized peptide derived from human PDLI2 AA range: 190-240
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.22% sodium azide.
背景
This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011],
