产品详情
This antibody detects endogenous levels of CPT1A at Human/Mouse/Rat
免疫原详细信息
Synthesized peptide derived from human CPT1A. AA range 40-80
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.346% sodium azide.
背景
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
