产品详情
This antibody detects endogenous levels of DGCR8 at Human/Mouse
免疫原详细信息
Synthesized peptide derived from human DGCR8 AA range: 467-517
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.348% sodium azide.
背景
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],