WB;ELISA

Cleaved-MMP-15 (Y132) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-15 protein resulting from cleavage adjacent to Y132.

The antiserum was produced against synthesized peptide derived from human MMP15. AA range:113-162

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression. [provided by RefSeq, Jan 2016],