产品详情
Phospho-TIP60 (S86) Polyclonal Antibody detects endogenous levels of TIP60 protein only when phosphorylated at S86.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human TIP60 around the phosphorylation site of Ser86. AA range:52-101
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008],