产品详情
Phospho-Bcl-6 (S333) Polyclonal Antibody detects endogenous levels of Bcl-6 protein only when phosphorylated at S333.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human Bcl-6 around the phosphorylation site of Ser333. AA range:299-348
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015],
