产品详情
HIF-3α Polyclonal Antibody detects endogenous levels of HIF-3α protein.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human HIF-3alpha. AA range:305-354
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
hypoxia inducible factor 3 alpha subunit(HIF3A) Homo sapiens The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011],