产品详情
This antibody detects endogenous levels of STAT4 (Phospho Ser721) Rabbit pAb at Human, Mouse
免疫原详细信息
Synthesized peptide derived from human STAT4 (Phospho Ser721)
相关试剂
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
背景
signal transducer and activator of transcription 4(STAT4) Homo sapiens The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],
