产品详情
Phospho-DRP1 (S637) Polyclonal Antibody detects endogenous levels of DRP1 protein only when phosphorylated at S637(human), S643(mouse), S656(rat), .
免疫原详细信息
Synthesized phospho-peptide around the phosphorylation site of human DRP1 (phospho Ser637)
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013],
