产品详情
Phospho-Ku-70 (S5) Polyclonal Antibody detects endogenous levels of Ku-70 protein only when phosphorylated at S5.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human Ku70 around the phosphorylation site of Ser5. AA range:1-50
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008],
