产品详情
Phospho-Casein Kinase Iγ1/2/3 (Y263) Polyclonal Antibody detects endogenous levels of Casein Kinase Iγ1/2/3 protein only when phosphorylated at Y263.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human CK-1 gamma1/2/3 around the phosphorylation site of Tyr263. AA range:229-278
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016],