产品详情
This antibody detects endogenous levels of ACE2 at Human, Mouse,Rat
免疫原详细信息
Synthesized peptide derived from human ACE2 AA range: 425-475
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.06% sodium azide.
背景
angiotensin I converting enzyme 2(ACE2) Homo sapiens The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
