产品详情
LRBA Polyclonal Antibody detects endogenous levels of protein.
免疫原详细信息
Synthesized peptide derived from human protein . at AA range: 1970-2050
相关试剂
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
背景
The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],
